Article

Early and accurate detection of ovarian cancer by profiling cell-free mitochondrial DNA fragmentomics in multi-ethnic population

2026-07-27

Abstract excerpt

Ovarian cancer (OC) remains highly lethal due to frequent late-stage diagnosis and the challenge of distinguishing malignant from benign adnexal masses (BAM) preoperatively. Reliable non-invasive diagnostic biomarkers remain an unmet clinical need. This multi-center study aimed to evaluate the diagnostic potential of plasma circulating cell-free mitochondrial DNA (ccf-mtDNA) fragmentomics for improving OC manageme...

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Literature Corpus work: b2abdd0f-6913-59bd-97ea-d4d6d01e3ffe
DOI: 10.1186/s13073-026-01735-6

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