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Plasma cfDNA methylation markers for the detection and prognosis of ovarian cancer

13 Aug 2022

Abstract excerpt

BACKGROUND: Plasma cell-free DNA (cfDNA) methylation has shown the potential in the detection and prognostic testing in multiple cancers. Herein, we thoroughly investigate the performance of cfDNA methylation in the detection and prognosis of ovarian cancer (OC). METHODS: The OC-specific differentially methylated regions (DMRs) were identified by sequencing ovarian tissue samples from OC (n = 61), benign ovarian...

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Share to Cancer Genomics and Diagnostics
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PMID: 35973389
DOI: 10.1016/j.ebiom.2022.104222

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