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Significance of Conserved Regions in Coronavirus Spike Protein for Developing a Novel Vaccine against SARS-CoV-2 Infection

24 Feb 2023

Abstract excerpt

Over the years, several distinct pathogenic coronaviruses have emerged, including the pandemic SARS-CoV-2, which is difficult to curtail despite the availability of licensed vaccines. The difficulty in managing SARS-CoV-2 is linked to changes in the variants' proteins, especially in the spike protein (SP) used for viral entry. These mutations, especially in the SP, enable the virus to evade immune responses...

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Animal Virus Infections Studies
SARS-CoV-2 and COVID-19 Research
Viral gastroenteritis research and epidemiology

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36992129
DOI: 10.3390/vaccines11030545

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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