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Computational design of a broad-spectrum multi-epitope vaccine candidate against seven strains of human coronaviruses

23 Aug 2022

Abstract excerpt

Abstract Spike (S) proteins are an attractive target as it mediates the binding of the SARS-CoV-2 to the host through ACE-2 receptors. We hypothesize that the screening of the S protein sequences of all the seven known HCoVs would result in the identification of potential multi-epitope vaccine candidates capable of conferring immunity against various HCoVs. In the present study, several machine learning-based...

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PMID: 36003896
DOI: 10.1007/s13205-022-03286-0

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