Article

Appropriate glycemic management protects the germline but not uterine environment in type 1 diabetes

2024-01-09

Abstract excerpt

Emerging evidence indicates that parental diseases can impact the health of subsequent generations through epigenetic inheritance. Recently, it was shown that maternal diabetes alters the metaphase II oocyte transcriptome, causing metabolic dysfunction in offspring. However, the type 1 diabetes (T1D) mouse models frequently utilized in previous studies may be subject to several confounding factors as a result of s...

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Literature Corpus work: b2879449-a1be-5378-9229-44c95878adc3
DOI: 10.1101/2024.01.09.574805

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