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Article

High-glucose concentrations change DNA methylation levels in human IVM oocytes

12 Jan 2018

Abstract excerpt

STUDY QUESTION: What are the effects of high-glucose concentrations on DNA methylation of human oocytes? SUMMARY ANSWER: High-glucose concentrations altered DNA methylation levels of Peg3 and Adiponectin in human in vitro maturation oocytes. WHAT IS KNOWN ALREADY: Maternal diabetes has a detrimental influence on oocyte quality including epigenetic modifications, as shown in non-human mammalian species. STUDY...

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Share to Epigenetics and DNA Methylation
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PMID: 29377995
DOI: 10.1093/humrep/dey006

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