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Effects of multisuperovulation on the transcription and genomic methylation of oocytes and offspring

28 Sept 2024

Abstract excerpt

BACKGROUND: Controlled ovarian stimulation is a common skill of assisted reproductive technologies (ARTs). In the clinic, some females would undergo more than one controlled ovarian stimulation cycle. However, few studies have focused on the influence of multi-superovulation on oocytes and offspring. RESULTS: Here, we found that multi-superovulation disrupted the transcriptome of oocytes and that the...

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PMID: 39342274
DOI: 10.1186/s13148-024-01746-3

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