Article

Pharmacological characterization of seven human histamine H <sub>3</sub> receptor isoforms

2023-12-11

Abstract excerpt

The histamine H 3 receptor (H 3 R) regulates as a presynaptic G protein-coupled receptor the release of histamine and other neurotransmitters in the brain, and is consequently a potential therapeutic target for neuronal disorders. The human H 3 R encodes for seven splice variants that vary in the length of intracellular loop 3 and/or the C-terminal tail but are all able to induce heterotrimeric G i protein sig...

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Literature Corpus work: b27895f0-d61c-515f-884d-eb1b6a16bcca
DOI: 10.1101/2023.12.06.570349

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