Article

IGF1 modulates lesional skin inflammation in checkpoint inhibitor-induced lichen planus

2026-05-28

Abstract excerpt

Immune checkpoint inhibitor-induced lichen planus (ICI-LP) is a cutaneous immune related adverse event (irAE) that shares key clinicopathologic features with spontaneous lichen planus (LP) but differs histologically and in the sex distribution of its incidence, and may therefore reflect a distinct tissue inflammatory state. To define the cellular programs that distinguish ICI-LP from LP, we profiled lesional skin...

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Literature Corpus work: b2571239-d091-5b0e-94dc-63f8650731b3
DOI: 10.64898/2026.05.27.726087

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