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Article

Multi-omics analysis unveiled fibroblast-mediated pathogenesis in male genital lichen sclerosus

31 Jul 2025

Abstract excerpt

Male genital lichen sclerosus (LS), a chronic inflammatory dermatological condition, has been recognized for its profound implications on the quality of life among males. The exact etiological factors behind this prevalent condition remained largely enigmatic. In this research, we employed a multi-omics strategy to identify and elucidate the underlying histological biomarkers and the fundamental pathogenesis...

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PMID: 40745572
DOI: 10.1186/s13578-025-01453-3

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