Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Spatial transcriptomics landscape of lesions from non-communicable inflammatory skin diseases

13 Dec 2022

Abstract excerpt

Abundant heterogeneous immune cells infiltrate lesions in chronic inflammatory diseases and characterization of these cells is needed to distinguish disease-promoting from bystander immune cells. Here, we investigate the landscape of non-communicable inflammatory skin diseases (ncISD) by spatial transcriptomics resulting in a large repository of 62,000 spatially defined human cutaneous transcriptomes from 31...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dermatology and Skin Diseases
Share to IL-33, ST2, and ILC Pathways
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36513651
DOI: 10.1038/s41467-022-35319-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Spatial transcriptomics landscape of lesions from non-communicable inflammatory skin diseasesPMID 36513651Read ↗

Low numbers of cytokine transcripts drive inflammatory skin diseases by initiating amplification cascades in localized epidermal clustersSemantic proximity Read ↗

Spatial transcriptomics reveals organized and distinct immune activation in cutaneous granulomatous disordersSemantic proximity Read ↗

Spatial transcriptomics stratifies psoriatic disease severity by emergent cellular ecosystemsSemantic proximity Read ↗

A Transcriptomic Atlas of Healthy Human Skin Links Regional Identity to Inflammatory DiseaseSemantic proximity Read ↗

Deconstruction of immune-mediated skin diseases defines six inflammatory subtypes.Semantic proximity Read ↗

Architecture of skin inflammation in psoriasis revealed by spatial transcriptomicsSemantic proximity Read ↗

A scRNA-seq atlas of chronic inflammatory skin diseasesSemantic proximity Read ↗

Maximizing the Utility of Transcriptomics Data in Inflammatory Skin DiseasesSemantic proximity Read ↗

A Spatially Coordinated Keratinocyte-Fibroblast Circuit Recruits MMP9 <sup>+</sup> Myeloid Cells to Drive IFN-I-Driven Inflammation in Photosensitive AutoimmunitySemantic proximity Read ↗

Multi-modal skin atlas identifies a multicellular immune-stromal community associated with altered cornification and specific T cell expansion in atopic dermatitisSemantic proximity Read ↗

Review—Current Concepts in Inflammatory Skin Diseases Evolved by Transcriptome Analysis: In-Depth Analysis of Atopic Dermatitis and PsoriasisSemantic proximity Read ↗

Hidden immune memory niches in inflammatory skin diseasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.