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Article

Lichen Sclerosus: An autoimmunopathogenic and genomic enigma with emerging genetic and immune targets

1 Jan 2019

Abstract excerpt

Lichen sclerosus (LS) is an inflammatory dermatosis with a predilection for anogenital skin. Developing lesions lead to vulvar pain and sexual dysfunction, with a significant loss of structural anatomical architecture, sclerosis, and increased risk of malignancy. Onset may occur at any age in both sexes, but typically affects more females than males, presenting in a bimodal fashion among pre-pubertal children and...

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PMID: 31337973
DOI: 10.7150/ijbs.34613

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