Article

Expression and localization of NMDA receptor GluN2 subunits in dorsal horn pain circuits across sex, species, and late postnatal development

2025-10-23

Abstract excerpt

<h4>ABSTRACT</h4> Despite being essential mediators of pain processing, the molecular identity of N-methyl-D-aspartate receptor (NMDAR) subtypes in nociceptive dorsal horn circuits is poorly understood, especially between sexes and in humans. Given the importance of GluN2 subunits in shaping NMDAR function and plasticity, we investigated the expression and localization of specific GluN2 NMDAR variants in the dors...

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Literature Corpus work: b1fdcbfe-4cfc-585d-bbf6-302f7b2c4163
DOI: 10.1101/2025.10.22.683915

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