Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Organoid cultures for the analysis of cancer phenotypes.

Current opinion in genetics & development - 1 Feb 2014

Sachs Norman, Clevers Hans

Abstract excerpt

Preclinical models of cancer are essential for a basic understanding of cancer biology and its translation into efficient treatment options for affected patients. Cancer cell lines and xenografts derived directly from primary human tumors have proven very valuable in fundamental oncology research and anticancer drug discovery. Both models inherently comprise advantages and caveats that have to be accounted for....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3D Printing in Biomedical Research
Share to Cancer Cells and Metastasis
Share to Cell Line, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasms

Share to Organoids

Share to Phenotype

Share to Tissue Culture Techniques

Share to Xenograft Model Antitumor Assays

Source

Identifiers

PMID: 24657539
DOI: 10.1016/j.gde.2013.11.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Organoid cultures for the analysis of cancer phenotypes.PMID 24657539Read ↗

Organoid Models for Cancer ResearchSemantic proximity Read ↗

Patient-derived organoids (PDOs) and PDO-derived xenografts (PDOXs): New opportunities in establishing faithful pre-clinical cancer modelsSemantic proximity Read ↗

Organoids in cancer research.Semantic proximity Read ↗

Tumor organoids in cancer medicine: from model systems to natural compound screeningSemantic proximity Read ↗

Establishing Pure Cancer Organoid Cultures: Identification, Selection and Verification of Cancer Phenotypes and GenotypesSemantic proximity Read ↗

Current concepts in tumour-derived organoidsSemantic proximity Read ↗

Application of cancer organoids: The forefront of personalized oncology and preclinical testingSemantic proximity Read ↗

Cancer research using organoid technologySemantic proximity Read ↗

Standardization of organoid culture in cancer researchSemantic proximity Read ↗

Three-Dimensional Organoids in Cancer Research: The Search for the Holy Grail of Preclinical Cancer ModelingSemantic proximity Read ↗

Patient-derived organoids in translational oncology and drug screeningSemantic proximity Read ↗

Organoids: Past Learning and Future DirectionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.