Article

Rapid reverse genetics systems for N. furzeri, a suitable model organism to study vertebrate aging

2022-06-02

Abstract excerpt

The African turquoise killifish ( N. furzeri ) is a useful model organism for studying aging, age-related diseases, and embryonic diapause. CRISPR/Cas9-mediated gene knockout and Tol2 transposon-mediated transgenesis in N. furzeri have been reported previously. However, these methods take time to generate knockout and transgenic fish. In addition, knock-in technology that inserts large DNA fragments as fluorescent...

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Literature Corpus work: b1bd7deb-a64f-50d4-938b-cca248917ca8
DOI: 10.21203/rs.3.rs-1467860/v1

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