Article
The hitchhiker's guide to Xenopus genetics.
Genesis (New York, N.Y. : 2000) - 1 Mar 2012
Abu-Daya Anita, Khokha Mustafa K, Zimmerman Lyle B
Abstract excerpt
A decade after the human genome sequence, most vertebrate gene functions remain poorly understood, limiting benefits to human health from rapidly advancing genomic technologies. Systematic in vivo functional analysis is ideally suited to the experimentally accessible Xenopus embryo, which combines embryological accessibility with a broad range of transgenic, biochemical, and gain-of-function assays. The diploid...
Topics
- Animals
- Chromosome Mapping
- Evolution, Molecular
- Genetic Association Studies
- Genetic Testing
- Humans
- Mutation
- Organogenesis
- Xenopus