Article

Transformation and allelic exchange in <i>Orientia tsutsugamushi</i>

2026-06-26

Abstract excerpt

<h4>ABSTRACT</h4> Orientia tsutsugamushi is a mite-transmitted obligate intracellular bacterium that causes the potentially deadly zoonosis, scrub typhus. The absence of genetic tools for Orientia have limited studies of the microbe-host interactions that underlie scrub typhus. To address this gap, we developed a protocol for transforming and achieving allelic exchange in O. tsutsugamushi str. Ikeda. From evalu...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b188db19-da96-53bd-aa2e-8e537b6b513e
DOI: 10.64898/2026.06.22.733791

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transformation and allelic exchange in <i>Orientia tsutsugamushi</i>DOI 10.64898/2026.06.22.733791Read

Long-read whole genome sequencing and comparative analysis of six strains of the human pathogen <i>Orientia tsutsugamushi</i>Semantic proximity Read

The Orientia tsutsugamushi genome reveals massive proliferation of conjugative type IV secretion system and host-cell interaction genes.Semantic proximity Read

Comparative virulence analysis of seven diverse strains of <i>Orientia tsutsugamushi</i> reveals a multifaceted and complex interplay of virulence factors responsible for diseaseSemantic proximity Read

Comparative Dual RNA-Seq Analysis of Eight <i>Orientia tsutsugamushi</i> Strains in Endothelial Cells Reveals Regulatory Patterns in Bacterial and Host Pathways During InfectionSemantic proximity Read

Comparative pan-genomic analyses of Orientia tsutsugamushi reveal an exceptional model of bacterial evolution driving genomic diversity.Semantic proximity Read

<i>Orientia tsutsugamushi:</i> analysis of the mobilome of a highly fragmented and repetitive genome reveals ongoing lateral gene transfer in an obligate intracellular bacteriumSemantic proximity Read

Targeted sequence capture of <i>Orientia tsutsugamushi</i> DNA from chiggers and humansSemantic proximity Read

Dissecting the developmental life cycle and developing genetic tools for understanding the biology of Orientia tsutsugamushiSemantic proximity Read

Peptidoglycan in Orientia tsutsugamushi and other Rickettsiales speciesSemantic proximity Read

Recent advances in genetic systems in obligate intracellular human-pathogenic bacteriaSemantic proximity Read

Long-read whole genome sequencing and comparative analysis of six strains of the human pathogen Orientia tsutsugamushi.Semantic proximity Read

Dual RNA-seq provides insight into the biology of the neglected intracellular human pathogen <i>Orientia tsutsugamushi</i>Semantic proximity Read