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Comparative pan-genomic analyses of Orientia tsutsugamushi reveal an exceptional model of bacterial evolution driving genomic diversity.

Microbial genomics - 1 Sept 2018

Fleshman Amy, Mullins Kristin, Sahl Jason, Hepp Crystal, Nieto Nathan, Wiggins Kristin, Hornstra Heidie, Kelly Daryl, Chan Teik-Chye, Phetsouvanh Rattanaphone, Dittrich Sabine, Panyanivong Phonepasith, Paris Daniel, Newton Paul, Richards Allen, Pearson Talima

Abstract excerpt

Orientia tsutsugamushi, formerly Rickettsia tsutsugamushi, is an obligate intracellular pathogen that causes scrub typhus, an underdiagnosed acute febrile disease with high morbidity. Scrub typhus is transmitted by the larval stage (chigger) of Leptotrombidium mites and is irregularly distributed across endemic regions of Asia, Australia and islands of the western Pacific Ocean. Previous work to understand...

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Share to Evolution, Molecular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30035711
DOI: 10.1099/mgen.0.000199
PMCID: PMC6202447

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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