Article
Recent advances in genetic systems in obligate intracellular human-pathogenic bacteria
19 Jun 2023
Abstract excerpt
The ability to genetically manipulate a pathogen is fundamental to discovering factors governing host–pathogen interactions at the molecular level and is critical for devising treatment and prevention strategies. While the genetic “toolbox” for many important bacterial pathogens is extensive, approaches for modifying obligate intracellular bacterial pathogens were classically limited due in part to the uniqueness...
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