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<i>Orientia tsutsugamushi:</i> analysis of the mobilome of a highly fragmented and repetitive genome reveals ongoing lateral gene transfer in an obligate intracellular bacterium

2023-05-11

Abstract excerpt

The rickettsial human pathogen Orientia tsutsugamushi (Ot) is an obligate intracellular Gram-negative bacterium with one of the most highly fragmented and repetitive genomes of any organism. Around 50% of its ∼2.3 Mb genome is comprised of repetitive DNA that is derived from the highly proliferated Rickettsiales amplified genetic element (RAGE). RAGE is an integrative and conjugative element (ICE) that is present...

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Literature Corpus work
58bc0b72-99e1-585b-a6b1-d48620e594c1
DOI
10.1101/2023.05.11.540415
Open publication

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