Runx1 regulates critical factors that control uterine angiogenesis and trophoblast differentiation during placental development

Abstract excerpt

Abstract During early pregnancy in humans and rodents, uterine stromal cells undergo a remarkable differentiation to form the decidua, a transient maternal tissue that supports the growing fetus. It is important to understand the key decidual pathways that orchestrate the proper development of the placenta, a key structure at the maternal–fetal interface. We discovered that ablation of expression of the...

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