Article

HAND1 knockdown disrupts trophoblast global gene expression

2022-11-01

Abstract excerpt

Congenital heart disease (CHD) affects nearly 1% of births annually, and CHD pregnancies carry increased risk of developing pathologies of abnormal placentation. We previously reported significant developmental impacts of disrupting Hand1 , a gene associated with CHD, expression in placenta trophoblast and endothelial cells in multiple mouse models. In this study, we aimed to build upon this knowledge and charact...

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Literature Corpus work: 270a1bdc-ea20-5020-88be-8611ad30ccd1
DOI: 10.1101/2022.11.01.514704

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