Advances in the biology and genetics of the podocytopathies: implications for diagnosis and therapy.

Abstract excerpt

CONTEXT: Etiologic factors and pathways leading to altered podocyte phenotype are clearly numerous and involve the activity of different cellular function. OBJECTIVE: To focus on recent discoveries in podocyte biology and genetics and their relevance to these human glomerular diseases, named podocytopathies. DATA SOURCES: Genetic mutations in genes encoding for proteins in the nucleus, slit diaphragm, podocyte...

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