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Genetically-regulated transcriptomics & copy number variation of proctitis points to altered mitochondrial and DNA repair mechanisms in individuals of European ancestry

2020-09-28

Abstract excerpt

<title>Abstract</title> <p><bold>BACKGROUND:</bold> Proctitis is an inflammation of the rectum and may be induced by radiation treatment for cancer. The genetic heritability of developing radiotoxicity and prior role of genetic variants as being associated with side-effects of radiotherapy necessitates further investigation for underlying molecular mechanisms. In this study, we investigated gene expression regula...

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Literature Corpus work
b1514845-a0de-5cf0-a45d-870022819327
DOI
10.21203/rs.3.rs-24270/v3
Open publication

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Genetically-regulated transcriptomics &amp; copy number variation of proctitis points to altered mitochondrial and DNA repair mechanisms in individuals of European ancestryDOI 10.21203/rs.3.rs-24270/v3
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