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Article

Association of DNA damage repair related genes with prostate cancer: A multi-omics Mendelian Randomization analysis.

Medicine - 29 May 2026

Xie Huadong, Ban Chengjie, Su Zhengwei, Huang Qingming, Tang Han, Cheng Zhi, Liao Tianling, Liao Kangji, Yi Xianlin

Abstract excerpt

The relationship between prostate cancer and DNA damage repair remains incompletely elucidated. This study employs Mendelian Randomization to explore the causal relationships between DNA Damage Repair-related gene methylation, expression, and protein abundance and prostate cancer risk. A comprehensive analysis was conducted on 2736 DNA Damage Repair-related genes identified from the GeneCards database using...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Neoplastic

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Source

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Identifiers

PMID: 42216412
DOI: 10.1097/MD.0000000000049185
PMCID: PMC13225592

Genes

POLI
RPA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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