Genome-wide transcriptomic response of whole blood to radiation

Abstract excerpt

Blood cells are affected in nearly all ionizing radiation exposure scenarios. Whole transcriptome data offer detailed insights into blood's radiation response, crucial for radiotherapy and biodosimetry. We conducted genome-wide RNA-seq analysis on blood from three donors irradiated ex vivo with X-rays and incubated for 2 h and 6 h. Gene expression was subject to strong inter-donor variation and time...

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