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A rare variant in ANP32B impairs influenza virus replication in human cells

2020-04-06

Abstract excerpt

<h4>ABSTRACT</h4> Viruses require host factors to support their replication, and genetic variation in such factors can affect susceptibility to infectious disease. Influenza virus replication in human cells relies on ANP32 proteins, which are involved in assembly of replication-competent dimeric influenza virus polymerase (FluPol) complexes. Here, we investigate naturally occurring single nucleotide variants (SNV...

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Identifiers and source

Literature Corpus work
b1482862-d1ce-567a-b3a5-e8047b36fb01
DOI
10.1101/2020.04.06.027482
Open publication

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A rare variant in ANP32B impairs influenza virus replication in human cellsDOI 10.1101/2020.04.06.027482
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