Article

Fundamental contribution and host range determination of ANP32 protein family in influenza A virus polymerase activity

2019-01-24

Abstract excerpt

<h4>ABSTRACT</h4> The polymerase of the influenza virus is part of the key machinery necessary for viral replication. However, the avian influenza virus polymerase is restricted in mammalian cells. The cellular protein ANP32A has been recently found to interact with viral polymerase, and to both influence polymerase activity and interspecies restriction. Here we report that either ANP32A or ANP32B is indispensabl...

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Literature Corpus work: 794199ee-9b38-5af4-bbdf-b7a1d9bbaff3
DOI: 10.1101/529412

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