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Article

Elucidating the Interactions between Influenza Virus Polymerase and Host Factor ANP32A

6 Nov 2019

Abstract excerpt

Successful zoonotic transmission of influenza A virus into humans can lead to pandemics in an immunologically naive population. Host-encoded ANP32A proteins are required to support influenza A virus polymerase activity, and species differences in ANP32A can restrict the host range of influenza virus. Understanding how ANP32A proteins support the viral polymerase and how differences in ANP32A affect the ability of...

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PMID: 31694956
DOI: 10.1128/jvi.01353-19

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