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Human gut microbiota interactions shape the long-term growth dynamics and evolutionary adaptations of <i>Clostridioides difficile</i>

2024-07-17

Abstract excerpt

<h4>ABSTRACT</h4> Clostridioides difficile can transiently or persistently colonize the human gut, posing a risk factor for infections. This colonization is influenced by complex molecular and ecological interactions with human gut microbiota. By investigating C. difficile dynamics in human gut communities over hundreds of generations, we show patterns of stable coexistence, instability, or competitive exclusion...

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Identifiers and source

Literature Corpus work
8a70601e-5d27-5c30-a4cd-551ca5fb883e
DOI
10.1101/2024.07.15.603560
Open publication

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