Article

How do bacterial extracellular Contractile Injection Systems bind target cells? A remarkable diversity of receptor binding domains

2025-05-13

Abstract excerpt

Extracellular contractile injection systems (eCISs) represent a diverse family of bacteriophage tail-derived toxin delivery complexes in prokaryotes. eCISs are vital for microbial interaction with hosts, and they use tail fiber proteins for target cell binding. However, the identity of the tail fiber proteins and their target cells are unknown. Here, we conducted a comprehensive exploration of eCIS tail fiber gene...

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Literature Corpus work: b130bf3c-9192-541b-9d9b-b7593b4c7a43
DOI: 10.1101/2025.05.13.653841

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