Article

Structural basis for repurposing a flexible phage tail into an Intraspecific bacterial competition weapon

2026-02-24

Abstract excerpt

The rise of multidrug-resistant bacteria poses a major threat to human health. Tailocins, which are phage tail-like bacteriocins, offer a way to kill specific bacteria without the risks of horizontal gene transfer found in phage therapy. While the mechanism of contractile R-type tailocins is well-established, the bactericidal action of non-contractile F-type tailocins remains unresolved. Here, we report the high-r...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3671d198-37d5-56b0-9cbf-5f63a1fcd3d4
DOI: 10.64898/2026.02.24.707460

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Structural basis for repurposing a flexible phage tail into an Intraspecific bacterial competition weaponDOI 10.64898/2026.02.24.707460Read

F-type Pyocins are Diverse Non-Contractile Phage Tail-Like Weapons for Killing <i>Pseudomonas aeruginosa</i>Semantic proximity Read

A broad-spectrum phage-encoded mechanism to disarm bacterial type IV filamentsSemantic proximity Read

Identification and Functional Insights into New Phage Tail-Like Bacteriocins (PTLBs) Targeting <i>Pseudomonas aeruginosa</i> as new antimicrobialsSemantic proximity Read

How do bacterial extracellular Contractile Injection Systems bind target cells? A remarkable diversity of receptor binding domainsSemantic proximity Read

TattleTail: A Pyocin Prediction ToolSemantic proximity Read

Cryo-EM analysis of Pseudomonas phage Pa193 structural componentsSemantic proximity Read

Targeting mechanisms of tailed bacteriophages.Semantic proximity Read

Molecular mechanism of bacteriophage tail contraction-structure of an S-layer-penetrating bacteriophageSemantic proximity Read

Pseudotyping Bacteriophage P2 Tail Fibers to Extend the Host Range for Biomedical ApplicationsSemantic proximity Read

«Study of 32 new phage tail-like bacteriocins (pyocins) from a clinical collection of Pseudomonas aeruginosa and of their potential use as typing markers and antimicrobial agents»Semantic proximity Read

Pyocin S5 import into <i>Pseudomonas aeruginosa</i> reveals a generic mode of bacteriocin transportSemantic proximity Read

Genomic evidence for widespread reciprocal recognition and killing among <i>Pseudomonas syringae</i> strainsSemantic proximity Read