Article
Targeting mechanisms of tailed bacteriophages.
Nature reviews. Microbiology - 1 Dec 2018
Nobrega Franklin L, Vlot Marnix, de Jonge Patrick A, Dreesens Lisa L, Beaumont Hubertus J E, Lavigne Rob, Dutilh Bas E, Brouns Stan J J
Abstract excerpt
Phages differ substantially in the bacterial hosts that they infect. Their host range is determined by the specific structures that they use to target bacterial cells. Tailed phages use a broad range of receptor-binding proteins, such as tail fibres, tail spikes and the central tail spike, to target their cognate bacterial cell surface receptors. Recent technical advances and new structure-function insights have...
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