Article

Large-scale discovery of candidate type VI secretion effectors with antibacterial activity

2021-10-07

Abstract excerpt

Type VI secretion systems (T6SS) are common bacterial contractile injection systems that inject toxic “effector” proteins into neighboring cells. Effector discovery is generally done manually, and computational approaches used for effector discovery depend on genetic linkage to T6SS genes and/or sequence similarity to known effectors. We bioinformatically investigated T6SS in more than 11,832 genomes of Gram negat...

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Literature Corpus work: 99e9b5c3-2a92-590d-832d-c3c20751eeae
DOI: 10.1101/2021.10.07.463556

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