Article

From binding to breakdown: biophysical and molecular insights into fluoroquinolone induced F-actin perturbation

2025-06-09

Abstract excerpt

<title>Abstract</title> <p>Neurodegenerative disorders involving actin dysregulation demand safer yet potent actin-disrupting compounds. Previous studies have reported the actin-destabilizing effects of fluoroquinolones (FQs), suggesting their potential for repurposing. FQs are widely prescribed broad-spectrum antibiotics known for their efficacy against bacterial infections. The newer generation FQs are also kno...

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Literature Corpus work: b126bc19-b9e7-5fe1-af25-d389aaf4acd7
DOI: 10.21203/rs.3.rs-6693104/v1

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