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Elevated blood pressure accelerates white matter brain aging among late middle-aged women: a Mendelian Randomization study in the UK Biobank

2023-04-12

Abstract excerpt

<h4>Background</h4> Elevated blood pressure (BP) is a modifiable risk factor associated with cognitive impairment and cerebrovascular diseases. However, the causal effect of BP on white matter (WM) brain aging remains unclear. <h4>Methods</h4> In this study, we focused on N=219,968 non-pregnant, family-unrelated individuals of European ancestry who had genotype data and two non-null clinical BP measurements availa...

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Literature Corpus work
b0d06989-fc18-5ea7-81a0-4cd02d58607b
DOI
10.1101/2023.04.06.23288211
Open publication

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Elevated blood pressure accelerates white matter brain aging among late middle-aged women: a Mendelian Randomization study in the UK BiobankDOI 10.1101/2023.04.06.23288211
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