Article

A novel analysis pipeline and experimental design for measuring expanded repeat instability

2026-03-15

Abstract excerpt

The expansion of short tandem repeats is a feature of over 60 different human diseases. Ongoing somatic instability throughout a patient’s lifetime can influence disease progression and has emerged as a therapeutic target. Understanding its mechanism is essential for the identification of both drug targets and therapeutic interventions. A major obstacle towards this translational goal has been to measure changes i...

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Literature Corpus work: b0b55aa5-6ad6-5337-bdde-5f11bbb22e28
DOI: 10.64898/2026.03.12.707943

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