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Article

A novel multiplexed, image-based approach to detect phenotypes that underlie chromosome instability in human cells.

PloS one - 1 Jan 2015

Thompson Laura L, McManus Kirk J

Abstract excerpt

Chromosome instability (CIN) is characterized by a progressive change in chromosome numbers. It is a characteristic common to virtually all tumor types, and is commonly observed in highly aggressive and drug resistant tumors. Despite this information, the majority of human CIN genes have yet to be elucidated. In this study, we developed and validated a multiplexed, image-based screen capable of detecting three...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 11

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Source

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Identifiers

PMID: 25893404
DOI: 10.1371/journal.pone.0123200
PMCID: PMC4404342

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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