Article

Common, low-frequency, rare, and ultra-rare coding variants contribute to COVID-19 severity

2021-09-14

Abstract excerpt

The combined impact of common and rare exonic variants in COVID-19 host genetics is currently insufficiently understood. Here, common and rare variants from whole exome sequencing data of about 4,000 SARS-CoV-2-positive individuals were used to define an interpretable machine learning model for predicting COVID-19 severity. Firstly, variants were converted into separate sets of Boolean features, depending on the a...

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Literature Corpus work: 2930ec46-ec59-5b3b-acb2-ab703f4147ca
DOI: 10.1101/2021.09.03.21262611

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