Article

Identification and small molecule rescue of mitochondrial dysfunction phenotype which converges across Leigh Syndrome and Huntington’s Disease patient fibroblasts

2026-06-08

Abstract excerpt

Mitochondrial dysfunction is implicated in a variety of complex neurological disorders. Primary mitochondrial diseases are caused directly by mutations in genes encoding mitochondrial proteins, leading to mitochondrial dysfunction and disease. Mitochondrial dysfunction is also a key contributor to pathogenesis in multiple neurodegenerative diseases. Rescue of mitochondrial function is therefore an attractive thera...

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Literature Corpus work: b036baa6-d914-5cc9-8d0a-710cb4a5e8cf
DOI: 10.64898/2026.06.08.730157

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