Article

DNA Vaccination Target on Amyloid Oligomer also Reduce tau Pathology and Improve Synaptic Function in Aged 3xTg-AD Mice

2020-10-19

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Active immunotherapy has been widely used as a potential therapeutic method for both treatment and prevention of Alzheimer’s disease (AD). Amyloid deposition and tau hyperphosphorylation are main pathological hallmarks of AD. Reduction in both is required to regulate synaptic proteins neurotransmission which can finally protect cognitive function. Growing eviden...

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Literature Corpus work: b02c526f-7f19-557f-9e84-294e3a88fcc3
DOI: 10.21203/rs.3.rs-92180/v1

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