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Article

[Treatment strategy of Alzheimer's disease: pause in clinical trials of Abeta vaccine and next steps].

Brain and nerve = Shinkei kenkyu no shinpo - 1 Jul 2010

Kuzuhara Shigeki

Abstract excerpt

The important pathognomonic features of Alzheimer disease (AD) brain are the occurrence of abundant neurofibrillary tangles (NFTs) in neurons and presence of extracellular deposits of beta-amyloid (Abeta)- senile plaques. In the early 1980s, the NFTs were characterized, and cerebral amyloid was purified; further the amino acid sequences of the tau protein in the NFTs and of Abeta were identified....

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Source

Identifiers

PMID: 20675870

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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