A novel bio-inspired strategy to prevent amyloidogenesis and synaptic damage in Alzheimer’s disease

Abstract excerpt

<title>Abstract</title> <p>Alzheimer’s disease (AD) is an irreversible neurodegenerative disorder that affects millions of people worldwide. AD pathogenesis is intricate. It primarily involves two main molecular players – amyloid-β (Aβ) and tau - which actually have an intrinsic trend to generate molecular assemblies that are toxic to neurons. Incomplete knowledge of the molecular mechanisms inducing the onset an...

Topics

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• Alzheimer Disease
• Amyloid beta-Peptides
• Amyloid beta-Protein Precursor
• Brain
• Global Health
• Immunologic Factors
• Incidence
• Practice Guidelines as Topic

Identifiers and source

Literature Corpus work

bd7d730c-ad07-5f71-80b9-31861fbf49cf

DOI

10.21203/rs.3.rs-1762247/v1