Article

Evidence for ABL amplification in multiple myeloma and therapeutic implications

2022-02-15

Abstract excerpt

<h4>Background: </h4> Cytogenetic abnormalities are considered initiating events in the pathogenesis of multiple myeloma (MM) and are assumed to be of clinical significance. <h4>Methods: </h4>: Fluorescence in situ hybridization (FISH) was used to analyze chromosomal architecture in 101 patients with MM. We evaluated overall patient survival and assessed cytotoxicity of imatinib against MM cells using a CCK8 assay...

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Literature Corpus work: b029ab36-7b1b-5ad4-99e7-5a43a2b32e81
DOI: 10.21203/rs.3.rs-48781/v3

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