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Detection of Genomic Abnormalities in Multiple Myeloma

26 Oct 2011

Abstract excerpt

Multiple myeloma (MM) is a hematopoietic neoplasm characterized by malignant plasma cells (PCs) that accumulate in the bone marrow. A number of different genomic abnormalities are associated with MM; however, detection of these by fluorescence in situ hybridization (FISH) can be limited by the percentage of PCs in the specimen. In this study, we tested 20 bone marrow specimens with known MM and a low...

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PMID: 22031309
DOI: 10.1309/ajcpf7nflw8uajep

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