Article
[New treatment and diagnostic test for multiple myeloma].
Rinsho byori. The Japanese journal of clinical pathology - 1 Apr 2014
Handa Hiroshi
Abstract excerpt
Multiple myeloma (MM) is a malignancy of plasma cells of the final maturation stage of B cells, characterized by atypical plasma cell proliferation in bone marrow and the production of monoclonal immunoglobulin. The history of chemotherapy for MM began in the early 1960s, when the efficacy of alkylating agents, particularly melphalan, was shown. High-dose therapy (HDT) has been the standard treatment for patients...
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