Back to search

Article

New generation prostate cancer therapy may impact motivation for exploration, spatial learning and dopaminergic transmission in aged castrated mice

2024-01-30

Abstract excerpt

<h4>Background: </h4> and Purpose: Cognitive side effects after cancer treatment threatening quality of life (QoL) constitute a major challenge in oncology. Abiraterone acetate plus prednisone (AAP) and enzalutamide (ENZ) are next generation therapy (NGT) administered with androgen deprivation therapy to metastatic castration-resistant prostate cancer (mCRPC) patients. NGT significantly improved mCRPC overall surv...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
aff8389d-00a6-5138-9b4a-ed2b859528c9
DOI
10.22541/au.170665184.42814756/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 11 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
New generation prostate cancer therapy may impact motivation for exploration, spatial learning and dopaminergic transmission in aged castrated miceDOI 10.22541/au.170665184.42814756/v1
The prostate cancer therapy enzalutamide compared with abiraterone acetate/prednisone impacts motivation for exploration, spatial learning and alters dopaminergic transmission in aged castrated miceSemantic proximity
Analysis of androgen receptor expression and activity in the mouse brainSemantic proximity
Cognitive impairment and associations with structural brain networks, endocrine status, and risk genotypes in patients with newly diagnosed prostate cancer referred to androgen-deprivation therapy.Semantic proximity
Androgen deprivation therapy and cognitive decline-associations with brain connectomes, endocrine status, and risk genotypes.Semantic proximity
Sex-Dependent Effects of Rivastigmine on Melatonin Receptors in Aged RatsSemantic proximity
Novel 5α-reductase inhibitors unlinked to depression-like phenotypes in rat model of BPH.Semantic proximity
Course and Predictors of Cognitive Function in Patients With Prostate Cancer Receiving Androgen-Deprivation Therapy: A Controlled Comparison.Semantic proximity
The role of melatonin deficiency induced by pinealectomy on motor activity and anxiety responses in young adult, middle-aged and old ratsSemantic proximity
Cannabinoid receptor 1 positive allosteric modulator ZCZ011 shows differential effects on behavior and the endocannabinoid system in HIV-1 Tat transgenic female and male miceSemantic proximity
Responses to environmental enrichment differ with sex and genotype in a transgenic mouse model of Huntington's disease.Semantic proximity
Cannabinoid receptor 1 positive allosteric modulator ZCZ011 shows differential effects on behavior and the endocannabinoid system in HIV-1 Tat transgenic female and male miceSemantic proximity
Select a neighboring publication to make it the new centre.