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The prostate cancer therapy enzalutamide compared with abiraterone acetate/prednisone impacts motivation for exploration, spatial learning and alters dopaminergic transmission in aged castrated mice

2021-04-02

Abstract excerpt

<h4>ABSTRACT</h4> Cognitive side effects after cancer treatment, threatening quality of life (QoL) and adherence to treatments, now constitute a major challenge in oncology. Abiraterone acetate plus prednisone (AAP) and enzalutamide (ENZ) are next generation therapy (NGT) administered with androgen deprivation therapy to metastatic castration-resistant prostate cancer (mCRPC) patients. NGT significantly improved...

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Literature Corpus work
357f4e0c-b9c3-5a22-8ff9-a5020d9098e3
DOI
10.1101/2021.04.01.438009
Open publication

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The prostate cancer therapy enzalutamide compared with abiraterone acetate/prednisone impacts motivation for exploration, spatial learning and alters dopaminergic transmission in aged castrated miceDOI 10.1101/2021.04.01.438009
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