Article

Dissecting heterogeneous cell populations across drug and disease conditions with PopAlign

2018-09-21

Abstract excerpt

Single-cell measurement techniques can now probe gene expression in heterogeneous cell populations from the human body across a range of environmental and physiological conditions. However, new mathematical and computational methods are required to represent and analyze gene expression changes that occur in complex mixtures of single cells as they respond to signals, drugs, or disease states. Here, we introduce a...

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Literature Corpus work: afd76f65-74ef-5675-b7f8-81b89ee2fe91
DOI: 10.1101/421354

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