Article

Functional Analysis of G6PD Variants Associated With Low G6PD Activity in the All of Us Research Program

2024-04-14

Abstract excerpt

<h4>ABSTRACT</h4> Glucose-6-phosphate dehydrogenase (G6PD) protects red blood cells against oxidative damage through regeneration of NADPH. Individuals with G6PD polymorphisms (variants) that produce an impaired G6PD enzyme are usually asymptomatic, but at risk of hemolytic anemia from oxidative stressors, including certain drugs and foods. Prevention of G6PD deficiency-related hemolytic anemia is achievable throu...

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Literature Corpus work: 506885ec-82bd-5109-9f1e-436456eb99c7
DOI: 10.1101/2024.04.12.24305393

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